Detalhe da pesquisa
1.
α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.
Proc Natl Acad Sci U S A
; 119(15): e2109617119, 2022 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35353605
2.
Uncovering a neurological protein signature for severe COVID-19.
Neurobiol Dis
; 182: 106147, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37178811
3.
Screening for Novel Inhibitors of Amyloid Beta Aggregation and Toxicity as Potential Drugs for Alzheimer's Disease.
Int J Mol Sci
; 24(14)2023 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511086
4.
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.
Brain
; 143(5): 1462-1475, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32380543
5.
Natural Alkaloid Compounds as Inhibitors for Alpha-Synuclein Seeded Fibril Formation and Toxicity.
Molecules
; 26(12)2021 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34205249
6.
Retraction Notice to: Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.
Mol Ther
; 2024 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608700
7.
Retraction Notice to: Corrigendum to "Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders".
Mol Ther
; 2024 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608701
8.
Antibodies against alpha-synuclein: tools and therapies.
J Neurochem
; 150(5): 612-625, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31055836
9.
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 129, 2018 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29716614
10.
Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration.
J Neuroinflammation
; 15(1): 169, 2018 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-29843738
11.
α-Synuclein species as potential cerebrospinal fluid biomarkers for dementia with lewy bodies.
Mov Disord
; 33(11): 1724-1733, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30440090
12.
Development of Nonviral Vectors Targeting the Brain as a Therapeutic Approach For Parkinson's Disease and Other Brain Disorders.
Mol Ther
; 24(4): 746-58, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700614
13.
Longitudinal changes in CSF alpha-synuclein species reflect Parkinson's disease progression.
Mov Disord
; 31(10): 1535-1542, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27548849
14.
Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology.
Neurobiol Dis
; 79: 81-99, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937088
15.
Structural insights into the unique recognition module between α-synuclein peptide and nanobody.
Protein Sci
; 33(2): e4875, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38105512
16.
Production of α-Synuclein Fibrillar-Specific scFv from Inclusion Bodies.
Methods Mol Biol
; 2617: 239-248, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36656529
17.
Auto-immunoproteomics analysis of COVID-19 ICU patients revealed increased levels of autoantibodies related to the male reproductive system.
Front Physiol
; 14: 1203723, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37520825
18.
Inhibition of α-Synuclein Seeding-Dependent Aggregation by ssDNA Aptamers Specific to C-Terminally Truncated α-Synuclein Fibrils.
ACS Chem Neurosci
; 13(23): 3330-3341, 2022 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36348612
19.
Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity.
FEBS J
; 289(15): 4657-4673, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35090199
20.
RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies.
Biomolecules
; 11(6)2021 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34072869